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AWWA JAW34163

M00002411

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AWWA JAW34163 Journal AWWA - Incorporating Biologically Based Models Into Assessments of Risk From Chemical Contaminants

Journal Article by American Water Works Association, 03/01/1993

Bull, Richard J.;Conolly, Rory B.;De Marini, David M.;MacPhail, Robert C.;Ohanian, Edward V.;Swenberg, James A.

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The general approach to assessment of risk from chemical contaminants in drinking water involves three steps: hazard identification, exposure assessment, and dose-response assessment. Traditionally, the risks to humans associated with different levels of a chemical have been derived from the toxic responses observed in animals. It is becoming increasingly clear, however, that further information is needed if risks to humans are to be assessed accurately. Biologically based models help clarify the dose-response relationship and reduce uncertainty. Includes 11 references.